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Immediate Benefits Consistent with JAMA Report on Clinical Decision Support

CAMBRIDGE, MA – February 22, 1999 – InterSystems Corporation today highlightedthe results achieved by the Provider Order-Entry System (POE) that recently wentlive at Massachusetts General Hospital (MGH) in Boston. The statistics, whichquantify the benefits that can be delivered by automating the order-entry processand enabling clinical decision support, were announced by InterSystems this weekat the HIMSS ’99 Conference and Exposition in Atlanta.

POE is the result of development efforts by Partners HealthCare System, Inc., an integrated healthcare delivery network that includes more than 4,000 Boston area physicians. Eclipsys Corporation (Nasdaq:ECLP) served as a development partner. The heritage of the clinical support application is a POE system originally implemented at Brigham and Women’s Hospital in Boston. Both the original order-entry system and MGH’s POE are built on the Caché post-relational database from InterSystems. All of the hospitals ranked in the top 10 in U.S. News & World Report magazine’s 1998 annual hospital survey use InterSystems database technology.

POE went live at MGH in October 1998 with multiple clinical decision support functions including automated checks for drug allergies, duplicate medication and laboratory orders, non-formulary medication reminders and departmental and personal order sets. Drug-drug interaction checking and food-drug interaction checking are slated for implementation in 1999. More than 6,000 orders from six medical units are entered daily. The benefits of automated decision support are tallying up rapidly. Based on figures from 4Q98, the MGH staff reports that a modest number of lab orders are triggering notification of duplication, leading to physicians canceling 17% of those orders. Other results show that, of the medication orders that trigger a duplication alert, 13% of these orders are canceled. Also, 1% of medication orders trigger allergy alerts, and 25% of those orders are canceled.

Results Match Findings Reported in JAMA

“These findings are consistent with the benefits of decision support that Partners HealthCare has documented at the Brigham,” says John Glaser, Partners HealthCare vice president and CIO. “In a two-part study conducted before and after the physician order-entry system went up, we found that serious medication errors went down by 55% after the system was installed. This application is possibly the most formidable tool we have to deliver high-quality care while controlling costs,” Glaser continues. The results of the study at the Brigham were recently published in an article in the Journal of the American Medical Association where David Bates, MD, and other Partners HealthCare colleagues documented the benefits they are achieving with clinical decision support.

“The success of the Brigham implementation and its positive impact on the quality of healthcare delivery drove the decision to develop a commercial product and bring it to market,” says Stephanie P. Massengill, Eclipsys Senior Vice President, Market Development. “Sunrise Clinical Manager, our commercial product based on the collaboration we’ve had with Partners HealthCare, significantly reduces medication errors that can pose a major accidental risk to hospital patients.”

InterSystems views the results at MGH as concrete evidence of the strides made in automated clinical decision support. “Partners HealthCare is known throughout the healthcare arena as a leader in leveraging the best information technology to deliver the highest quality care,” says Paul Grabscheid, InterSystems vice president of strategic planning. “We applaud the results of their partnership with Eclipsys and will actively support the Eclipsys initiative to bring Sunrise Clinical Manager to market.”

About InterSystems

Headquartered in Cambridge, MA, InterSystems Corporation ( is the leading provider of high performance database systems, with over two million users worldwide. InterSystems’ flagship product, Caché, is a post-relational database with a multidimensional data server. Offering ultra-fast SQL and advanced object architecture, Caché delivers breakthrough time-to-market technology for massively scalable Web and client-server applications.

About Eclipsys

Eclipsys Corporation is a Delray Beach, FL-based healthcare information-technology company providing integrated information software and service solutions to the healthcare industry, partnering with its customers to help them improve clinical, financial and satisfaction outcomes. The company’s new Sunrise™ product line is a multi-tiered, database-neutral, browser-enabled suite of rules-oriented applications that provide real-time clinical decision support and emphasize direct physician knowledge-based order entry. Sunrise also supports managed care and multi-entity processing for IHN integrated combined business offices (CBOs). Products can be purchased in combination to provide an enterprise-wide solution or individually to address specific needs. Eclipsys also provides a wide range of outsourcing, remote processing and networking services to meet the information-technology needs of its customers.

Trademark Notes: Caché is a trademark of InterSystems Corporation. Sunrise is a trademark of Eclipsys Corporation. Other trademarks belong to their respective owners.

Editorial Contacts:

Rita Shoor
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InterSystems Marketing
InterSystems Corporation
(617) 621-0600