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New Détente Molecular Genetics Lab System Goes Live

Eton, UK—May 6, 2003—InterSystems has announced that Great Ormond Street Hospital (GOSH), London has gone live with a new molecular genetics laboratory management system powered by CACHÉ post-relational database technology. The Web-enabled application, developed by Australia-based Détente Systems, allows the hospital’s 3,000 clinicians to view test information on the ward, with appropriate security, the moment it becomes available – and gives quick and easy access to huge volumes of data to aid the hospital’s world-leading research into, and management of, childhood disorders.

The renowned children’s hospital, linked with the Institute for Children’s Health, is known as a leading authority in this increasingly high profile field, receiving samples for DNA testing from all over the world and holding data on around half a million patients. Through its pioneering research and extensive data held, the hospital is able to identify and monitor those whose genetic make-up mean they are likely to inherit diseases, so extending and even saving lives.

But as Peter Miller, GOSH pathology systems manager explains, it is not so much the number of tests, but the complexity which generates such a significant volume of data.

“As an eminent centre for research we are currently using data going back as far as 1988 – we don’t intend to archive! One patient’s record can hold information on as many as 10,000 episodes and each different test can have 20 – 30 reference sites so you can tell the degree of sophistication needed,” he says.

“We needed a system with a robust, extremely reliable and flexible database with high performance transaction processing. CACHÉ post-relational database technology stores data in a multidimensional structure – ideal for complex laboratory data that needs to be accessed quickly. Plus, this also means the system performs exceptionally well in 24-hour operation; vital at GOSH where everything is urgent.”

Great Ormond Street had been using a Détente OMNI-Lab system for around four years but the need to develop a system to manage genetics testing was a major driver to upgrade.

The genetics application, which runs on an HP clustered PC server has been built on top of the OMNI-Lab pathology system – a move which Miller finds significant: “It demonstrates for the first time how genetics is being brought into mainstream lab testing – and how the results are now being used throughout the hospital.”

The new system can be accessed through around 130 work stations within the labs and by all clinical staff via a Web browser from every PC throughout the hospital. This means results are made available and can be acted upon as soon as the tests are completed. Clinical staff are also automatically notified of test results by email.

“We are delighted that Détente chose to develop this prestigious application using CACHÉ,” says Graham Frost, InterSystems UK managing director. “The vast majority of both primary and secondary healthcare applications in use in the UK already run on InterSystems platforms. As demands on lab management systems increase, we believe that even more application developers will find that CACHÉ offers the database and development environment required to create the reliable, high-performance, low maintenance systems that are vital to successful healthcare applications.”

About Détente

Headquartered in Sydney, Australia, Détente Systems ( is a specialised health software developer of complete Laboratory and Radiology information systems with clients in Australia, New Zealand and United Kingdom. Détente’s products (OMNI-Lab and OMNI-Image) provide leading Laboratory and Radiology solutions to individual hospitals and private clinics and regional networked partnerships irrespective of operational size.

About InterSystems

Headquartered in Cambridge, Mass., InterSystems Corporation ( is a leading provider of high performance, low-maintenance database systems for Web applications, with over four million users worldwide. InterSystems’ flagship product, CACHÉ, is a post-relational database that uniquely offers three integrated data access options: a robust object database, high performance SQL, and rich multidimensional access. CACHÉ enables rapid Web application development, extraordinary transaction processing speed and real time queries against transactional data.

InterSystems is the leading database provider in healthcare, with CACHÉ in use at the majority of major hospitals and labs around the world, including America’s 10 best hospitals as rated by U.S. News and World Report.

Trademark Notes:  Caché is a trademark of InterSystems Corporation.  Other trademarks belong to their respective owners.

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