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Products
By Type
By Industry
Applications
A suite of applications built on InterSystems IRIS data platform and optimized to address industry specific challenges.
A FHIR®-enabled care management software solution that allows the entire care team to create and share comprehensive care plans.
A cloud-based, on-demand service delivering near real-time, secure access to patient data from across the nation.
Analytics solution that provides real-time care insights and in-depth analysis for clinical, business, and population health management.
A next-generation enterprise master person index – an automated, easily integrated solution for identity resolution.
A reimagined EHR with built-in GenAI that empowers clinicians, enhances patient experiences, and elevates business operations.
Helps clinicians, care managers, and care teams strengthen coordination, enhance continuity of care, and improve patient engagement in under-served rural areas.
Enables health systems, independent providers, health plans, HIEs, governments and software developers to create a digital front door.
Collects, consolidates, and publishes information about healthcare providers' relationships to patients, health plans, and one another.
A powerful, flexible electronic health record (EHR) that supports all leading health information interoperability standards and profiles.
Enterprise solution supports any clinical lab service, public or private, independent to extensive national laboratory systems.
Low Code Platforms
A suite of low code platforms built on InterSystems IRIS and optimized to address industry-specific challenges.
An aggregated, normalized and deduplicated patient record created from patient data across multiple sources.
A high-availability, high-performance integration engine created specifically for healthcare.
A cloud-based data pipeline and management solution combining FHIR with an out-of-the-box transformation to the CDM and OMOP repository.
One integration that standardizes data exchange between Epic Payer Platform and your clinical and administrative applications.
Interoperability solutions designed to help U.S. health insurers address CMS-0057 and CMS-9115.
Platforms & Components
Versatile foundation supporting a range of solutions, with built-in APIs for integration.
Rapidly access & use FHIR data from diverse sources without the need to create your own FHIR computing infrastructure.
A high-performance data platform designed to make it easy to build applications that support mission-critical processes.
Fully managed cloud-native SaaS offerings that provide customers the fastest time to value for InterSystems data management software.
A digital health data platform that provides the building blocks needed to work with any healthcare data standard, including FHIR.
An AI-enabled supply chain decision intelligence platform that predicts disruptions before they occur, and optimally handles when they do.
Healthcare
InterSystems HL7 FHIR-based technology and solutions power success for organizations across the entire healthcare ecosystem.
A cloud-based, on-demand service delivering near real-time, secure access to patient data from across the nation.
A suite of solutions that work together to capture information, share it in a meaningful way, aid understanding, and drive transformative action.
Analytics solution that provides real-time care insights and in-depth analysis for clinical, business, and population health management.
Rapidly access & use FHIR data from diverse sources without the need to create your own FHIR computing infrastructure.
A high-availability, high-performance integration engine created specifically for healthcare.
A reimagined EHR with built-in GenAI that empowers clinicians, enhances patient experiences, and elevates business operations.
A digital health data platform that provides the building blocks needed to work with any healthcare data standard, including FHIR.
A cloud-based data pipeline and management solution combining FHIR with an out-of-the-box transformation to the CDM and OMOP repository.
One integration that standardizes data exchange between Epic Payer Platform and your clinical and administrative applications.
Interoperability solutions designed to help U.S. health insurers address CMS-0057 and CMS-9115.
Helps clinicians, care managers, and care teams strengthen coordination, enhance continuity of care, and improve patient engagement in under-served rural areas.
A powerful, flexible electronic health record (EHR) that supports all leading health information interoperability standards and profiles.
Enterprise solution supports any clinical lab service, public or private, independent to extensive national laboratory systems.
Financial Services
Enabling firms to transform at scale, so they can increase customer satisfaction, adopt generative AI, maintain compliance, grow revenue, and optimize efficiency.
A high-performance data platform designed to make it easy to build applications that support mission-critical processes.
The fastest way for financial services firms to break down silos and transform disparate data into a single unified resource of actionable information.
Launch new funds, accelerate AI initiatives, automate reporting with a self-service solution tailor-made for asset management firms.
Supply Chain
Empowering organizations with real-time supply chain visibility and the ability to make optimized, real-time, AI-driven decisions.
An AI-enabled supply chain decision intelligence platform that predicts disruptions before they occur, and optimally handles when they do.
A data gateway that speeds and simplifies data access for supply chain applications and practitioners.
Knowledge Hub
Developer Websites
New to InterSystems? Start here, this is your gateway to developer sites, tutorials and more.
Connect, grow, share. The developer community is full of resources, news, and events and a community of people to connect with.
Everything you need to know about our products and more.
Develop. Learn. Share. Network. All with InterSystems Global Masters program where you can join an engaged community of developers.
Experience first hand the community’s dedication to the evolution of our technology with applications.
Education
Get to know InterSystems products and technologies your way, with self-paced online materials and classroom courses.
Online learning presents self-paced materials to help you build and support your organization's most critical applications.
In-person courses maximize learning in a distraction-free environment with face-to-face engagement.
InterSystems proudly supports the free use of InterSystems products for university and college coursework.
View the full list of course offerings and our current course schedule.
Certification
Offers industry-standard exams, flexible testing options, certification badges, and career advancement opportunities demonstrating expertise in InterSystems technologies.
InterSystems Learning Services offers industry-standard certification exams that allow you to prove your mastery of our technology.
Digital credentials that represent the varying levels of achievement you can earn with InterSystems.
Everything you need to know about preparing for, scheduling, and taking InterSystems Exams.
Retake Policies & Support, Beta Exams and more.
Answers to common questions regarding exams, including exam preparation, practice exams, retaking exams, and certifications.
InterSystems Blogs
Explore InterSystems blogs featuring expert insights, industry trends, technology innovations, data management strategies, and thought leadership.
Healthcare industry experts talk about pressing challenges, issues, and trends at the intersection of healthcare and technology.
Addressing various business, data, and technology-related issues for the line of business.
Partners
Partner Programs
Our partners ensure that organizations around the globe are already ready for tomorrow’s opportunities.
Bring together people, processes and technology to deliver solutions that solve complex customer challenges.
Combine your expertise with our proven data, analytics and interoperability capabilities to deliver optimal solutions.
Specialists whose services and guidance ensure consistent, effective delivery of InterSystems technology.
Provide complementary tools and platforms that strengthen and expand our technologies' capabilities.
InterSystems powers data-driven digital startups across healthcare, financial services, and supply chain.
Cloud Partners
InterSystems works with the world's leading cloud providers to give customers the freedom to deploy our technology where it delivers the most value.
The speed, scale, and capabilities of InterSystems and AWS can streamline operations, improve access to data and power breakthrough applications.
InterSystems IRIS and InterSystems IRIS for Health Data Platforms are Preferred Solutions on Azure Marketplace.
InterSystems and Google Cloud empower you to quickly build new apps or modernize existing ones to increase agility and reap the benefits of the multicloud.
InterSystems works with the world’s leading cloud providers - including Amazon Web Services (AWS), Microsoft Azure, Google Cloud, TenCent and Alibaba
Company
About Us
Our technologies provide the connective tissue that transforms disparate data into a single, complete view, enabling better outcomes.
News
News and resources for media including press releases, media kits, tools and more.
The latest news and coverage from our corporate headquarters in Boston, MA.
Core information about InterSystems, our background, our products and technologies, and more.
Please contact Corporate Affairs & Communications regarding media inquiries.
Events
Check out conferences and events we're hosting and attending, and view on-demand content for anything you missed.
Browse our upcoming conference and event schedule to see where we'll be and what we'll be covering.
View our library of on-demand content, including keynote speeches from InterSystems READY, webinars and live event footage.
Watch keynote presentations from InterSystems READY 2026.
Support
Product Support
We provide expert technical assistance to customers 24 hours a day, every day, with support advisors in 15 countries.
Read about support alerts, critical issues, fixes, and product releases.
Access current and previous versions and related notes for InterSystems products.
Contact the WRC for Immediate Help
Documentation
Detailed technical information for InterSystems products, technologies, solutions, and more.
Products
By Type
By Industry
Applications
A suite of applications built on InterSystems IRIS data platform and optimized to address industry specific challenges.
A FHIR®-enabled care management software solution that allows the entire care team to create and share comprehensive care plans.
A cloud-based, on-demand service delivering near real-time, secure access to patient data from across the nation.
Analytics solution that provides real-time care insights and in-depth analysis for clinical, business, and population health management.
A next-generation enterprise master person index – an automated, easily integrated solution for identity resolution.
A reimagined EHR with built-in GenAI that empowers clinicians, enhances patient experiences, and elevates business operations.
Helps clinicians, care managers, and care teams strengthen coordination, enhance continuity of care, and improve patient engagement in under-served rural areas.
Enables health systems, independent providers, health plans, HIEs, governments and software developers to create a digital front door.
Collects, consolidates, and publishes information about healthcare providers' relationships to patients, health plans, and one another.
A powerful, flexible electronic health record (EHR) that supports all leading health information interoperability standards and profiles.
Enterprise solution supports any clinical lab service, public or private, independent to extensive national laboratory systems.
Low Code Platforms
A suite of low code platforms built on InterSystems IRIS and optimized to address industry-specific challenges.
An aggregated, normalized and deduplicated patient record created from patient data across multiple sources.
A high-availability, high-performance integration engine created specifically for healthcare.
A cloud-based data pipeline and management solution combining FHIR with an out-of-the-box transformation to the CDM and OMOP repository.
One integration that standardizes data exchange between Epic Payer Platform and your clinical and administrative applications.
Interoperability solutions designed to help U.S. health insurers address CMS-0057 and CMS-9115.
Platforms & Components
Versatile foundation supporting a range of solutions, with built-in APIs for integration.
Rapidly access & use FHIR data from diverse sources without the need to create your own FHIR computing infrastructure.
A high-performance data platform designed to make it easy to build applications that support mission-critical processes.
Fully managed cloud-native SaaS offerings that provide customers the fastest time to value for InterSystems data management software.
A digital health data platform that provides the building blocks needed to work with any healthcare data standard, including FHIR.
An AI-enabled supply chain decision intelligence platform that predicts disruptions before they occur, and optimally handles when they do.
Healthcare
InterSystems HL7 FHIR-based technology and solutions power success for organizations across the entire healthcare ecosystem.
A cloud-based, on-demand service delivering near real-time, secure access to patient data from across the nation.
A suite of solutions that work together to capture information, share it in a meaningful way, aid understanding, and drive transformative action.
Analytics solution that provides real-time care insights and in-depth analysis for clinical, business, and population health management.
Rapidly access & use FHIR data from diverse sources without the need to create your own FHIR computing infrastructure.
A high-availability, high-performance integration engine created specifically for healthcare.
A reimagined EHR with built-in GenAI that empowers clinicians, enhances patient experiences, and elevates business operations.
A digital health data platform that provides the building blocks needed to work with any healthcare data standard, including FHIR.
A cloud-based data pipeline and management solution combining FHIR with an out-of-the-box transformation to the CDM and OMOP repository.
One integration that standardizes data exchange between Epic Payer Platform and your clinical and administrative applications.
Interoperability solutions designed to help U.S. health insurers address CMS-0057 and CMS-9115.
Helps clinicians, care managers, and care teams strengthen coordination, enhance continuity of care, and improve patient engagement in under-served rural areas.
A powerful, flexible electronic health record (EHR) that supports all leading health information interoperability standards and profiles.
Enterprise solution supports any clinical lab service, public or private, independent to extensive national laboratory systems.
Financial Services
Enabling firms to transform at scale, so they can increase customer satisfaction, adopt generative AI, maintain compliance, grow revenue, and optimize efficiency.
A high-performance data platform designed to make it easy to build applications that support mission-critical processes.
The fastest way for financial services firms to break down silos and transform disparate data into a single unified resource of actionable information.
Launch new funds, accelerate AI initiatives, automate reporting with a self-service solution tailor-made for asset management firms.
Supply Chain
Empowering organizations with real-time supply chain visibility and the ability to make optimized, real-time, AI-driven decisions.
An AI-enabled supply chain decision intelligence platform that predicts disruptions before they occur, and optimally handles when they do.
A data gateway that speeds and simplifies data access for supply chain applications and practitioners.
Knowledge Hub
Developer Websites
New to InterSystems? Start here, this is your gateway to developer sites, tutorials and more.
Connect, grow, share. The developer community is full of resources, news, and events and a community of people to connect with.
Everything you need to know about our products and more.
Develop. Learn. Share. Network. All with InterSystems Global Masters program where you can join an engaged community of developers.
Experience first hand the community’s dedication to the evolution of our technology with applications.
Education
Get to know InterSystems products and technologies your way, with self-paced online materials and classroom courses.
Online learning presents self-paced materials to help you build and support your organization's most critical applications.
In-person courses maximize learning in a distraction-free environment with face-to-face engagement.
InterSystems proudly supports the free use of InterSystems products for university and college coursework.
View the full list of course offerings and our current course schedule.
Certification
Offers industry-standard exams, flexible testing options, certification badges, and career advancement opportunities demonstrating expertise in InterSystems technologies.
InterSystems Learning Services offers industry-standard certification exams that allow you to prove your mastery of our technology.
Digital credentials that represent the varying levels of achievement you can earn with InterSystems.
Everything you need to know about preparing for, scheduling, and taking InterSystems Exams.
Retake Policies & Support, Beta Exams and more.
Answers to common questions regarding exams, including exam preparation, practice exams, retaking exams, and certifications.
InterSystems Blogs
Explore InterSystems blogs featuring expert insights, industry trends, technology innovations, data management strategies, and thought leadership.
Healthcare industry experts talk about pressing challenges, issues, and trends at the intersection of healthcare and technology.
Addressing various business, data, and technology-related issues for the line of business.
Partners
Partner Programs
Our partners ensure that organizations around the globe are already ready for tomorrow’s opportunities.
Bring together people, processes and technology to deliver solutions that solve complex customer challenges.
Combine your expertise with our proven data, analytics and interoperability capabilities to deliver optimal solutions.
Specialists whose services and guidance ensure consistent, effective delivery of InterSystems technology.
Provide complementary tools and platforms that strengthen and expand our technologies' capabilities.
InterSystems powers data-driven digital startups across healthcare, financial services, and supply chain.
Cloud Partners
InterSystems works with the world's leading cloud providers to give customers the freedom to deploy our technology where it delivers the most value.
The speed, scale, and capabilities of InterSystems and AWS can streamline operations, improve access to data and power breakthrough applications.
InterSystems IRIS and InterSystems IRIS for Health Data Platforms are Preferred Solutions on Azure Marketplace.
InterSystems and Google Cloud empower you to quickly build new apps or modernize existing ones to increase agility and reap the benefits of the multicloud.
InterSystems works with the world’s leading cloud providers - including Amazon Web Services (AWS), Microsoft Azure, Google Cloud, TenCent and Alibaba
Company
About Us
Our technologies provide the connective tissue that transforms disparate data into a single, complete view, enabling better outcomes.
News
News and resources for media including press releases, media kits, tools and more.
The latest news and coverage from our corporate headquarters in Boston, MA.
Core information about InterSystems, our background, our products and technologies, and more.
Please contact Corporate Affairs & Communications regarding media inquiries.
Events
Check out conferences and events we're hosting and attending, and view on-demand content for anything you missed.
Browse our upcoming conference and event schedule to see where we'll be and what we'll be covering.
View our library of on-demand content, including keynote speeches from InterSystems READY, webinars and live event footage.
Watch keynote presentations from InterSystems READY 2026.
Support
Product Support
We provide expert technical assistance to customers 24 hours a day, every day, with support advisors in 15 countries.
Read about support alerts, critical issues, fixes, and product releases.
Access current and previous versions and related notes for InterSystems products.
Contact the WRC for Immediate Help
Documentation
Detailed technical information for InterSystems products, technologies, solutions, and more.
Search to learn about InterSystems products and solutions, career opportunities, and more.

Ensuring High Availability, Performance, Security, and Scalability for the Leading Nationwide Public Health Data Exchange

eHealth Exchange

doctor with tablet

COMPANY: eHealth Exchange national health information network

CHALLENGE: Interconnect tens of thousands of distinct healthcare entities across the United States

OUTCOME: Fast, reliable, and secure data exchange nationwide 

eHealth Exchange, the largest health information network in the United States, uses InterSystems solutions to power its massively scalable eHealth Exchange Hub data platform. InterSystems cloud-hosted managed service offerings help eHealth Exchange accelerate time-to-value and ensure outstanding performance and availability for its nationwide data-sharing network.

eHealth Exchange facilitates over 21 billion secure transactions a year and is known as the network of choice for public health and the federal government. It provides connectivity for 60 regional and state health information exchanges (HIEs), 75% of U.S. hospitals and health systems, 6 TEFCA national health information networks, 70,000 medical groups, 85% of dialysis centers, payers in 34 states, as well as countless urgent care centers, surgery centers, and clinical laboratories. Public health agencies nationwide, as well as five federal agencies, rely on eHealth Exchange to share patient information with private-sector partners and among each other. eHealth Exchange also connects to 35+ national health information networks via Carequality.

eHealth Exchange is one of the inaugural electronic data-sharing networks in the country to be designated as a Qualified Health Information Network™ (QHIN™) under the Trusted Exchange Framework and Common Agreement™ (TEFCA™). Created under the 21st Century Cures Act, TEFCA establishes a universal governance, policy, and technical foundation for nationwide interoperability. eHealth Exchange stands apart from other designated and approved-candidate QHINs as the only network that connects healthcare providers to five different federal agencies and supports the routing of electronic case reports (eCRs) to public health agencies in all 50 states.

Improving Patient Care and Public Health

eHealth Exchange connects federal agencies and non-federal healthcare organizations throughout the United States. The network dramatically improves patient care and public health by ensuring tens of thousands of organizations with disparate systems can share vital medical data—quickly, reliably, and securely.

eHealth Exchange makes it easy for organizations with disparate systems to exchange healthcare information
eHealth Exchange makes it easy for organizations with disparate systems to exchange healthcare information

A hub-and-spoke architecture lets eHealth Exchange participants exchange patient data via a single connection, a single set of APIs, and one trust agreement for ultimate convenience, ease-of-deployment, and economics.

Accelerating the Pace of Innovation with InterSystems

Since 2019, eHealth Exchange has relied on a number of InterSystems solutions including InterSystems IRIS for Health™ and InterSystems HealthShare™ to power eHealth Exchange Hub, the centerpiece of its electronic data-sharing network. InterSystems solutions help eHealth Exchange efficiently connect diverse networks and entities, and reliably exchange data at high scale with ultra-low latency.

InterSystems cloud-based, fully managed solutions help eHealth Exchange accelerate time-to-market for new use cases, avoid upfront capital equipment expenditures, and tightly align ongoing expenses with evolving business requirements. The solutions make it easy for healthcare organizations to get connected and become TEFCA-compliant.

eHealth Exchange and InterSystems

“With InterSystems we can support new data exchange use cases quickly and cost-effectively to help our members expand information sharing and keep pace with change,” explains Jay Nakashima, President at eHealth Exchange. “InterSystems helps us reduce operations expense and complexity, and free up technical resources to focus on more strategic tasks.”

InterSystems solutions support every healthcare data standard, including HL7® FHIR®. They help eHealth Exchange optimize system performance and availability, and lay the foundation for emerging FHIR projects. The eHealth Exchange Hub underpins a variety of innovative public health data exchange applications including a FHIR-based adverse events monitoring application, an automated electronic case reporting application, and a nationwide disaster preparedness and response application.

Jay Nakashima, President,
eHealth Exchange

Automating Adverse Event Monitoring

eHealth Exchange Hub is the cornerstone of the U.S. FDA Biologics Effectiveness and Safety (BEST) exchange platform, one of the first national-scale, FHIR-based public health exchanges in the world. Live in 46 states, the platform handles millions of FHIR R4 transactions annually for the FDA’s adverse events reporting program. The AI-based program automates inefficient manual processes and provides more robust monitoring of adverse events, while minimizing the burden on providers.

FDA BEST Exchange Platform powered by eHealth Exchange and InterSystems diagram
FDA BEST Exchange Platform powered by eHealth Exchange and InterSystems

The BEST platform supports two distinct adverse event use cases: a “push scenario” to intelligently detect and validate adverse event cases and report them to the FDA via eHealth Exchange; and a “pull scenario” to automatically gather patient data from provider EHR systems for validation purposes by the FDA.

Streamlining Electronic Case Reporting

eHealth Exchange participants can automatically send eCRs to appropriate local, state, and national public health agencies via eHealth Exchange’s partnership with the Association of Public Health Laboratories (APHL), an eHealth Exchange participant. Many participants started leveraging the solution to report COVID-19 cases at the onset of the pandemic. Today, providers can automatically share over 80+reportable diseases via eHealth Exchange.

Empowering Clinicians at Disaster Sites

The Patient Unified Lookup System for Emergencies (PULSE) is a nationwide health IT disaster response platform deployed at the city, county, or state level to authenticate and empower volunteer clinicians at disaster sites. With an eHealth Exchange connection, authorized volunteers in makeshift “pop-up” clinics and elsewhere can use PULSE to retrieve patient medical records and make well-informed decisions.

InterSystems and eHealth Exchange

InterSystems helps eHealth Exchange provide fast, reliable, and secure data exchanges nationwide. The QHIN-designated network works tirelessly to advance interoperability through new use cases to serve the public good, enhance workflows, and reduce administrative burdens. With these efficiencies, eHealth Exchange is transforming care and improving outcomes.

eHealth Exchange is using InterSystems solutions to streamline information sharing for value-based care and to operationalize the HL7 Da Vinci Project, including a hub-and-spoke model for electronic prior authorization and clinical data exchange (CDEX).

Jay Nakashima, President
eHealth Exchange

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