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Mark Pasquale, CEO of the Missouri Health Connection (MHC) and a guest speaker at the 2015 Global Healthcare Leadership Conference, discusses how the InterSystems HealthShare informatics platform links information in many different formats for true interoperability. MHC, a public health information exchange (HIE) serving Missouri and neighboring states, used the platform to create MHC CareNet, where participants now access real-time medical information. HealthShare supports all of the on-demand functions that have become increasingly important over the last 18 to 24 months.